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Posted: Friday, October 19, 2018GLC-Biology Seminar: 'Biomechanics of Establishing Asymmetries during Embryo Development' - October 22
Please join the Biology Department and the Great Lakes Center for the seminar "Biomechanics of Establishing Asymmetries during Embryo Development," presented by Jeffrey Amack, associate professor in the Department of Cell and Developmental Biology at SUNY Upstate Medical University, on Monday, October 22, from 3:00 to 4:15 p.m. in Bulger Communication Center 424 (West 2). All students, staff, and faculty are welcome.
Abstract
Vital internal organs develop asymmetries along the left-right (LR) body axis. Disruption of this LR asymmetry can result in a broad spectrum of birth defects. Evidence from several vertebrates (human, mouse, frog, and zebra fish) indicates an embryonic structure referred to as the "left-right organizer" (LRO) activates signals that guide asymmetric organ development; however, the mechanisms that control form and function of the LRO are poorly understood. We are using mathematical models and in vivo experiments in zebra fish embryos to identify biochemical signals and mechanical forces that influence LRO function and organ development.
