The Daily Bulletin Archive

Please join the Biology Department for the seminar "Is Your Cornea on Drugs? Bringing the Bedside to the Bench," presented by Sangita P. Patel, clinical instructor and research assistant professor with the Ross Eye Institute and UB Department of Ophthalmology, on Monday, November 16, at 3:00 p.m. in Bulger Communication Center West.

All faculty, staff, and students are welcome.

Abstract
Our broad research goal is to understand the physiology of fluid transport in the cornea, the clear dome on the front of the eye that serves as the eye’s primary refracting surface. The posterior layer of the cornea, the corneal endothelium, has a “pump” function to maintain the optimal hydration of the cornea to prevent corneal edema and maintain clarity. Active ion transport and solute fluxes underlie the “pump” function, but the full molecular identities of the components and mechanism of coordinated action remain an enigma. In this presentation, I will discuss how clinical observations are driving our bench research to understand the physiology of the corneal endothelium.