The Daily Bulletin Archive

Please join the Biology Department for the seminar "Blood Cell Production, Immunity, and Inflammation: A Unique Glycoscience Perspective," presented by Joseph Lau, distinguished research professor in the Department of Molecular and Cellular Biology at Roswell Park Cancer Institute, on Monday, October 20, from 3:30 to 4:30 p.m. in Technology Building 160.

All faculty, staff, and students are welcome.

Seminar Abstract
Glycans occupy the critical junction between the inside and outside of cells, through which all signals communicating cell behavior must be conveyed. All blood cells are generated from precursor blood stem cells under strict instructions to properly resupply all blood cell lineages, including red cells for oxygen transport, platelets to stop bleeding, and white cells to endow immunity and inflammation to combat infections and injury. Glycoscience is the study of the glycans. We are driven by the hypothesis that manipulation of the glycans can dramatically alter the way cells receive and interpret external signals. Therefore, this property can be leveraged to bring about novel paradigms in treatment and diagnosis of clinically relevant maladies, including cancer and inflammatory conditions.  Recent findings relating to manipulating glycans and blood cells will be discussed.