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Posted: Tuesday, October 9, 2012

Fall 2012 Chemistry/Physics Seminar: 'Rapid Screening of Oral Fluids in the Detection of Illicit Drugs'

Sandra Jones, a graduate student in the forensic science program at Buffalo State, will present a literature seminar, "Rapid Screening of Oral Fluids in the Detection of Illicit Drugs," at 12:30 p.m. Thursday, October 11, in Science Building 272. The seminar abstract is as follows:

Rapid oral fluid detection may prove to be a reliable indicator of recent use of a wide range of abused drugs. During this talk, the principles and efficacy of rapid screening of oral fluid for illicit and abused drugs will be discussed. This talk will first demonstrate whether oral fluid can be as effective as other biological fluids for testing drugs of abuse. The validity of the screening devices and methods for rapid oral fluid detection will be presented by comparing their results with those obtained with exhaustive and conclusive tests involving GC-MS or LC-MS. The sensitivity and accuracy of oral fluid test kits proved favorable as compared with industry standard methods. Finally, the prospect of screening devices for the drug test will be provided.

References

Crooks, R. C.; Brown, S. (2010). Roche DAT Immunoassay: Sensitivity and specificity testing for amphetamines, cocaine, and opiates in oral fluid. J. Anal. Toxicol. 34, 103109.

Gandhi, S.; Sharma, P.; Capalash, N. (2008). Group-selective antibodies based fluorescence immunoassay for monitoring opiate drugs. Anal. Bioanal. Chem. 39, 215222.

Pehrsson, A.; Blencowe, T.; Vimpari, K.; Langel, K.; Engblom, C.; Lillsunde, P. (2011). An evaluation of on-site oral fluid DrugWipe 5+ and Rapid STAT using oral fluid for confirmation analysis. J.  Anal. Toxicol.  211218.

Samyn, N.; Laloup, M.; De Boeck, G. (2007). Bioanalytical procedure for determination of drugs of abuse in oral fluid. Anal. Bioanal. Chem. 14371453.

Submitted by: Jinseok Heo
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